Midnight Run is a volunteer service program which began in 1988. It focuses on the particular needs of the hungry and homeless people living in the community around Marquette. This program is organized by a coordinating team of Marquette students under the supervision of Campus Ministry. Volunteers serve meals and work in area meal programs and shelters. Service in Midnight Run is meant to challenge students to integrate their experiences with their faith. Midnight Run's philosophy is rooted in the gospel, with Matthew chapter 25 serving as its hallmark. Midnight Run is based on the fundamental belief in the dignity and worth of all persons and strives to cultivate a sense of responsibility for caring for all members of our community.

For over 20 years, the campus ministry program Midnight Run has utilized voluntary direct service (primarily nutrition and meal outreach) as its primary tool to “build relationships, and walk with those who are hungry, homeless, or suffer the consequences of society's unjust structures, honoring the dignity and worth of all.” Through reflection on service Midnight Run seeks to create men and women of service and develop agents of positive social change.