The social ministries are active year-round and open to all parishioners to join in making the social mission of the church the essential and central mission of the parish.  Examples of ministries include: parish twinning with St Jude's parish in Haiti, ongoing social justice eduation programs, and fair trade coffee sales.

Gesu Social Concerns Committee oversees a number of programs to the homeless including a regular Saturday meal program, Sunday breakfast bags. Gesu parishioners also partner with downtown congregations offering shelter and day programs to the homeless individuals and families and Gesu parishioners were instrumental in the establishment of a Milwaukee Housing Trust Fund

Midnight Run is a volunteer service program which began in 1988. It focuses on the particular needs of the hungry and homeless people living in the community around Marquette. This program is organized by a coordinating team of Marquette students under the supervision of Campus Ministry. Volunteers serve meals and work in area meal programs and shelters. Service in Midnight Run is meant to challenge students to integrate their experiences with their faith. Midnight Run's philosophy is rooted in the gospel, with Matthew chapter 25 serving as its hallmark. Midnight Run is based on the fundamental belief in the dignity and worth of all persons and strives to cultivate a sense of responsibility for caring for all members of our community.

For over 20 years, the campus ministry program Midnight Run has utilized voluntary direct service (primarily nutrition and meal outreach) as its primary tool to “build relationships, and walk with those who are hungry, homeless, or suffer the consequences of society's unjust structures, honoring the dignity and worth of all.” Through reflection on service Midnight Run seeks to create men and women of service and develop agents of positive social change.