Dolores Mission became a parish in 1945, after twenty years as a mission for nearby
St. Mary's Parish. By then, public housing had become a fixture of the neighborhood.
In 1980, the Society of Jesus (the Jesuits) came to the parish in response to a
request from Cardinal Timothy Manning, the archbishop of Los Angeles at the time.

The Kino Border Initiative provides pastoral assistance, shelter, breakfast and other assistance to recently deported migrants on the border in Nogales, AZ. In addition to these basic services, the Centro de Atencion a Migrantes Deportados (CAMDEP) provides overnight shelter to unaccompanied women who may need time and pastoral attention as they discern their next steps.

Nativity Fellows are full-time members of the Nativity staff. They teach an average of 2-4 class periods per day while serving as advisors, tutors, proctors, coaches, nurses, janitors, drivers, monitors and all other responsibilities that promote the success of the students’ well-being.

Casa Maria is the community house where fellows serving in Worcester's Nativity School reside.  Life in Casa Maria is an opportunity to form community and to engage in the tough work of sharing responsibility with each other for the myriad details which make life together possible and worth the effort. It is also a unique opportunity to engage in “simple living. ”Simple living" offers Nativity Fellows a chance to “feel” what life on a tight budget means, particularly as the overwhelming majority of Nativity families struggle to make ends meet. The Casa Maria Community attempts to gain a deeper sense of the difficult conditions from which Nativity students come.